Criteria Specification (CSpec) Registry is intended to provide access to the Criteria Specifications used and applied by ClinGen Variant Curation Expert Panels and biocurators in the classification of variants.
For general information about the ClinGen Expert Panels and Variant Curation please visit: Clinical Domain Working Groups. For specific inquiries regarding content correction or adding a new criteria specification refer to the Help page.
Should you encounter any issues regarding the data displayed, lack of functionality or other problems, please let us know by contacting us via email.
Launch of Criteria Specification EditorWe have launched Criteria Specification (CSpec) Editor. See more details about this on the CSpec Registry Version History page.
Launch of Criteria Specification RegistryWe have launched Criteria Specification (CSpec) Registry with Specifications from 14 approved Variant Curation Expert Panels. See more details about this on the CSpec Registry Version History page.